Evidence Based Research on

AUTOLOGOUS STEM CELL THERAPY

Autologous Stem Cell Therapy facts:

The word Autologous means derived from recipient receiving graft.


A stem cell is an unspecified cell that can both self-renew (reproduce itself) and differentiate into mature cells/tissues such as collagen, skin, cartilage, heart, lung, and pancreas.


Stem cells can be collected from peripheral blood or bone marrow.


Peripheral Blood stem cells are easier and less painful to collect than Bone Marrow stem cells.


Peripheral Blood collection also yields more stem cells than bone marrow collection.


ARTICLES

 

Click here to read about: The effects of autologus platelet rich plasma and various growth factors on non-transplanted miniaturized hair.

 

Click here to read about: Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome.

 

Click here to read about: Effects of Haematopoietic Autologous Stem Cell Transplantation To The Chronically Injured Human Spinal Cord Evaluated By Motor and Somatosensory Evoked Potentials Methods.

 

Click here to read about: Stem Cell Transplant in Rodents cure Progeeria a genetic disorder of premature aging. - PITTSBURGH TRIBUNE-REVIEW

 

Click here to read about: Stem Cell Transplant in mice counters aging and extends life span. - FoxNews.com

 

Click here to read about: Stem Cell transplant in mice confers significant lifespan and helathsapn. - Nature Communications 3, Article number: 608

 

Click here to read about: Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages - www.regenocyte.com

 

 

Stem Cells Provide Alternative to Hip Replacement Surgery

Researchers show how it may be possible to use a patient's own stem cells to grow new cartilage in the shape of a hip joint.


The utilization of stem cells in the medical industry captures the attention of critics, while opening the door to new medical discoveries. Healthcare professionals are focusing on a new type of treatment (hip replacement) using stem cells, to rebuild cartilage and restore bone density. This new discovery could put an end to traditional hip replacement therapy.

Unlike most cells in the body, stem cells are unspecialized, meaning they have the potential to transform into another type of cell, with special functions under the right physiologic and experimental conditions. These are the same cells that are typically found in bone marrow, and are common in hip replacement therapy.

How Does the Process Work?

stem cell image

The process begins with harvested stem cells taken from the bone marrow with a biopsy needle, and then centrifuged to create a concentrated formula. The formula containing the stem cell mixture is then injected into the hip joint, followed by an injection of rich plasma platelet. This injection will ultimately provide cartilage growth support, which is mandatory for new hip joint tissues.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases acclaims that the primary cause of hip replacement is a damaged hip joint, and osteoarthritis. The procedure removes the diseased portion of the hip, and replaces these parts with brand new prosthetic parts.

Statistics and Hip Replacement Therapy

Over 332,000 hip replacements are performed in the United States each year. The good news is that the replacement can last an average of 20 years. However, doctors are reluctant about performing hip replacement surgery on patients under 50 years of age. Nevertheless, it is likely that younger patients will need another hip replacement, within this time frame.

Researchers now realize that new cartilage is grown from a patient’s own biological stem cells, which are extracted from fat found under the skin. The process of growing the new cartilage in 3-D involves using a scaffold made of synthetic, which can be molded or shaped into the exact dimension of a patient’s hip joint.

To create the exact dimensions, the scaffold is created using nearly 600 organic bundles of woven fiber to perform like normal cartilage. By inserting one gene into newly grown cartilage, the effects can release anti- inflammatory properties, which aids in the relief of arthritis pain, and prevent the disease from reoccurring.

Benefits of Stem Cell Therapy Vs Knee Replacement Surgery

Healthcare professionals and researchers are confident in their belief that stem cell therapy provides the needed alternative doctors and patients are looking for. With traditional surgery becoming more and more obsolete, patients are looking for long-term solutions with short-term consequences. As of now, the testing phase is limited to animal testing. If all goes well, humans can expect a medical breakthrough, within the next three to five years.

It is predicted that the younger population may be ideal candidates for the new and upcoming biological hip or joint replacement, due to sports, degenerative bone diseases and severe arthritis. The key to a successful therapy is to identify, isolate and treat the condition. In this case, the end results are to reduce the high levels of pain-causing molecules, and protect the newly formed cartilage, while promoting long-term performance.

View News Source...


Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing, Farshid Guilak et al., Proceedings of the National Academy of Sciences, doi: 10.1073/pnas.1601639113, published online July 2016, abstract.

 

 






(Some of these procedures are in the experimental stage and are not the present standard of care, but all of these procedures are established under Federal Rules 21 CFR 1271.15 (b) and the California B&P Code section 2053.5.). This Institute does NOT use collagenase.