The word Autologous means derived from recipient receiving graft.
A stem cell is an unspecified cell that can both self-renew (reproduce itself) and differentiate into mature cells/tissues such as collagen, skin, cartilage, heart, lung, and pancreas.
Stem cells can be collected from peripheral blood or bone marrow.
Peripheral Blood stem cells are easier and less painful to collect than Bone Marrow stem cells.
Peripheral Blood collection also yields more stem cells than bone marrow collection.
Effects of Haematopoietic Autologous Stem Cell Transplantation To The Chronically Injured Human Spinal Cord Evaluated By Motor and Somatosensory Evoked Potentials Methods.
Frolov AA, Bryukhovetskiy AS
Cell Transplant. 2012 Mar 27.
20 adult patients with chronic spinal cord injury at C4-C8 level were examined by the Somatosensory Evoked Potentials (SEPs) and Motor Evoked Potentials (MEPs) method, first time prior to the treatment, and then regularly during its course (1-4 years). The treatment consisted of repeated intrathecal transplantations of autologous hematopoietic stem cells. Results: After at least 1 year of treatment, four effects were detected: 1. restoration of the initially absent short-latency SEP (3 patients); 2. N20P23 interpeak amplitude increase in SEP elicited by median nerve stimulation (4 patients); 3. P38 latency reduction in SEP elicited by tibial nerve stimulation (2 patients); 4. Appearance of MEP (3 patients). The local effects of stem cell treatment at the cervical level were evaluated by median SEP and wrist muscle MEP demonstrate the ability of stem cells to spread within the spinal cord at least from lumbar to the cervical level, home there and participate in the neurorestoration processes.
PMID: 22469672 [PubMed - as supplied by publisher]